Tongue Drops Effective For Ragweed Allergies?

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MADISON, Wis. — Oral allergy drops delivered under the tongue could be a safe and effective alternative to controlling ragweed pollen allergies, according to a recent study.

“While the drops haven’t been subjected to rigorous clinical trials in the United States yet, the early results are quite encouraging,” says Dr. Robert Bush, professor emeritus of medicine at the School of Medicine and Public Health and one of the investigators on the multi-site study involving 115 patients.


Europeans have been using the therapy for years, but in the U.S. it has been approved only for research and clinical trials so far.

Study results showed that symptom frequency decreased for those who were given high doses of the medication, as did the need to take additional medication.

The therapy seemed to work best in patients who react to a single allergen – such as ragweed pollen – rather than several.

“We don’t know how long people would need to be treated or the proper dose levels yet,” says Bush. “But it’s clear there’s a lot of interest in this therapy.”

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